全部产品分类
品牌 |
Leading Biology | 货号 |
AMM07907G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SNX13 antibody (C-term).
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分子量 |
112189 Da
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细胞定位 |
Antigen Cellular Localization:
Early endosome membrane; Peripheral membrane protein; Cytoplasmic side
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
780-807 aa
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靶点 |
This SNX13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 780-807 amino acids from the C-terminal region of human SNX13.
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亚型 |
Rabbit Ig
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通用名 |
KIAA0713
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基因ID |
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UniProt ID |
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功能 |
May be involved in several stages of intracellular trafficking. May play a role in endosome homeostasis (By similarity). Acts as a GAP for Galphas.
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总结 |
This gene encodes a PHOX domain- and RGS domain-containingprotein that belongs to the sorting nexin (SNX) family and theregulator of G protein signaling (RGS) family. The PHOX domain is aphosphoinositide binding domain, and the SNX family members areinvolved in intracellular trafficking. The RGS family members areregulatory molecules that act as GTPase activating proteins for Galpha subunits of heterotrimeric G proteins. The RGS domain of thisprotein interacts with G alpha(s), accelerates its GTP hydrolysis,and attenuates G alpha(s)-mediated signaling. Overexpression ofthis protein delayes lysosomal degradation of the epidermal growthfactor receptor. Because of its bifunctional role, this protein maylink heterotrimeric G protein signaling and vesicular trafficking.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:1000
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别名 |
Sorting nexin-13, RGS domain- and PHOX domain-containing protein, RGS-PX1, SNX13, KIAA0713
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图像 |
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说明书 |
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数量 |
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