全部产品分类
品牌 |
Leading Biology | 货号 |
APR07182G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SMPD1 antibody (C-term).
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分子量 |
69752 Da
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细胞定位 |
Antigen Cellular Localization:
Lysosome.
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
391-419 aa
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靶点 |
This SMPD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 391-419 amino acids from the C-terminal region of human SMPD1.
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亚型 |
Rabbit Ig
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通用名 |
ASM
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基因ID |
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UniProt ID |
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功能 |
Converts sphingomyelin to ceramide. Also has phospholipase C activities toward 1,2-diacylglycerolphosphocholine and 1,2-diacylglycerolphosphoglycerol. Isoform 2 and isoform 3 have lost catalytic activity.
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总结 |
The protein encoded by this gene is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide. The encoded protein also has phospholipase C activity. Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB). Multiple transcript variants encoding different isoforms have been identified. [provided by RefSeq].
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
FC, WB, IHC-P, E
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稀释方法 |
FC~~1:25
WB~~1:2000
IHC-P~~1:10~50
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别名 |
Sphingomyelin phosphodiesterase, Acid sphingomyelinase, aSMase, SMPD1, ASM
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图像 |
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说明书 |
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数量 |
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