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MSI1 Antibody (N-term)

AMM06492G Product Datasheet Protocol

货号	货期	规格 / 价格	询价
AMM06492G		100 μl / ￥4950

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MSI1 Antibody (N-term)

品牌	Leading Biology	货号	AMM06492G
产品分类	Polyclonal Antibodies	研究领域
产品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MSI1 antibody (N-term).
分子量	39125 Da
细胞定位	Antigen Cellular Localization: Cytoplasm. Nucleus
宿主	Rabbit
种属反应性	Human
免疫原	67-93 aa
靶点	This MSI1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 67-93 amino acids from the N-terminal region of human MSI1.
亚型	Rabbit Ig
基因ID	4440
UniProt ID	O43347
功能	RNA binding protein that regulates the expression of target mRNAs at the translation level. Regulates expression of the NOTCH1 antagonist NUMB. Binds RNA containing the sequence 5'- GUUAGUUAGUUAGUU-3' and other sequences containing the pattern 5'- [GA]U(1-3)AGU-3'. May play a role in the proliferation and maintenance of stem cells in the central nervous system (By similarity).
总结	This gene encodes a protein containing two conservedtandem RNA recognition motifs. Similar proteins in other speciesfunction as RNA-binding proteins and play central roles inposttranscriptional gene regulation. Expression of this gene hasbeen correlated with the grade of the malignancy and proliferativeactivity in gliomas and melanomas. A pseudogene for this gene islocated on chromosome 11q13.
形式	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
储存条件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
应用	WB, IHC-P, FC, E
稀释方法	WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50
别名	RNA-binding protein Musashi homolog 1, Musashi-1, MSI1
图像	Western blot analysis of lysate from SH?SY5Y cell line, using MSI1 Antibody (N-term)(Cat. AMM06492G). AMM06492G was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug per lane. MSI1 Antibody (N-term) (Cat. AMM06492G)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MSI1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. MSI1 Antibody (N-term) (Cat. AMM06492G) flow cytometric analysis of CEM cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
说明书	Product Datasheet Protocol
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