全部产品分类
品牌 |
Leading Biology | 货号 |
APR16918G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality ITGA8 antibody (C-term).
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分子量 |
117474 Da
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细胞定位 |
Antigen Cellular Localization:
Membrane; Single-pass type I membrane protein Cell membrane
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
1025-1053 aa
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靶点 |
This ITGA8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1025-1053 amino acids from the C-terminal region of human ITGA8.
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亚型 |
Rabbit Ig
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基因ID |
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UniProt ID |
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功能 |
Integrin alpha-8/beta-1 functions in the genesis of kidney and probably of other organs by regulating the recruitment of mesenchymal cells into epithelial structures. It recognizes the sequence R-G-D in a wide array of ligands including TNC, FN1, SPP1 TGFB1, TGFB3 and VTN. NPNT is probably its functional ligand in kidney genesis. Neuronal receptor for TNC it mediates cell-cell interactions and regulates neurite outgrowth of sensory and motor neurons.
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总结 |
Integrin alpha-8/beta-1 functions in the genesis of kidney and probably of other organs by regulating the recruitment of mesenchymal cells into epithelial structures. It recognizes the sequence R-G-D in a wide array of ligands including TNC, FN1, SPP1 TGFB1, TGFB3 and VTN. NPNT is probably its functional ligand in kidney genesis. Neuronal receptor for TNC it mediates cell-cell interactions and regulates neurite outgrowth of sensory and motor neurons.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC-P, E
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稀释方法 |
WB~~1:1000
IHC-P~~1:50~100
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别名 |
Integrin alpha-8, Integrin alpha-8 heavy chain, Integrin alpha-8 light chain, ITGA8
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图像 |
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说明书 |
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数量 |
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