全部产品分类
品牌 |
Leading Biology | 货号 |
APR11623G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality COCH antibody (C-term).
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分子量 |
59483 Da
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细胞定位 |
Antigen Cellular Localization:
Secreted, extracellular space, extracellular matrix
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
492-520 aa
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靶点 |
This COCH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 492-520 amino acids from the C-terminal region of human COCH.
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亚型 |
Rabbit Ig
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通用名 |
COCH5B2
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基因ID |
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UniProt ID |
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功能 |
Plays a role in the control of cell shape and motility in the trabecular meshwork.
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总结 |
The protein encoded by this gene is highly conserved inhuman, mouse, and chicken, showing 94% and 79% amino acid identityof human to mouse and chicken sequences, respectively.Hybridization to this gene was detected in spindle-shaped cellslocated along nerve fibers between the auditory ganglion andsensory epithelium. These cells accompany neurites at the habenulaperforata, the opening through which neurites extend to innervatehair cells. This and the pattern of expression of this gene inchicken inner ear paralleled the histologic findings of acidophilicdeposits, consistent with mucopolysaccharide ground substance, intemporal bones from DFNA9 (autosomal dominant nonsyndromicsensorineural deafness 9) patients. Mutations that cause DFNA9 havebeen reported in this gene. Alternative splicing results inmultiple transcript variants encoding the same protein. Additionalsplice variants encoding distinct isoforms have been described buttheir biological validities have not been demonstrated. [providedby RefSeq].
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:1000
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别名 |
Cochlin, COCH-5B2, COCH, COCH5B2
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图像 |
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说明书 |
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数量 |
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