全部产品分类
品牌 |
Leading Biology | 货号 |
APR14791G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality ACTL7A antibody (N-term).
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分子量 |
48644 Da
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细胞定位 |
Antigen Cellular Localization:
Cytoplasm, cytoskeleton. Golgi apparatus. Cytoplasm. Nucleus. Note=Detected at the Golgi apparatus during acrosome biogenesis. Detected at the subacrosomal layer in round spermatids. Detected in sperm head and tail (By similarity)
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
41-67 aa
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靶点 |
This ACTL7A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 41-67 amino acids from the N-terminal region of human ACTL7A.
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亚型 |
Rabbit Ig
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基因ID |
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UniProt ID |
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总结 |
ACTL7A is a member of a familyof actin-related proteins (ARPs) which share significant amino acidsequence identity to conventional actins. Both actins and ARPs havean actin fold, which is an ATP-binding cleft, as a common feature.The ARPs are involved in diverse cellular processes, includingvesicular transport, spindle orientation, nuclear migration andchromatin remodeling. ACTL7A (ACTL7A), and related gene, ACTL7B,are intronless, and are located approximately 4 kb apart in ahead-to-head orientation within the familial dysautonomia candidateregion on 9q31. Based on mutational analysis of the ACTL7A gene inpatients with this disorder, it was concluded that it is unlikelyto be involved in the pathogenesis of dysautonomia. The ACTL7A geneis expressed in a wide variety of adult tissues, however, its exactfunction is not known.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:1000
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别名 |
Actin-like protein 7A, Actin-like-7-alpha, ACTL7A
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图像 |
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说明书 |
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数量 |
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