品牌 |
Leading Biology | 货号 |
AMM07712G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SAR1B antibody (Center).
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分子量 |
22410 Da
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细胞定位 |
Antigen Cellular Localization:
Endoplasmic reticulum membrane; Peripheral membrane protein. Golgi apparatus, Golgi stack membrane; Peripheral membrane protein. Note=Associated with the endoplasmic reticulum and Golgi stacks, in particular in the juxta-nuclear Golgi region.
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
89-116 aa
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靶点 |
This SAR1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 89-116 amino acids from the Central region of human SAR1B.
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亚型 |
Rabbit Ig
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通用名 |
SARA2, SARB
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基因ID |
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UniProt ID |
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功能 |
Involved in transport from the endoplasmic reticulum to the Golgi apparatus. Activated by the guanine nucleotide exchange factor PREB. Involved in the selection of the protein cargo and the assembly of the COPII coat complex.
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总结 |
The protein encoded by this gene is a small GTPase thatacts as a homodimer. The encoded protein is activated by theguanine nucleotide exchange factor PREB and is involved in proteintransport from the endoplasmic reticulum to the Golgi. This proteinis part of the COPII coat complex. Defects in this gene are a causeof chylomicron retention disease (CMRD), also known as Andersondisease (ANDD). Two transcript variants encoding the same proteinhave been found for this gene.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
IHC-P, WB, FC, E
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稀释方法 |
IHC-P~~1:50~100
WB~~1:1000
FC~~1:10~50
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别名 |
GTP-binding protein SAR1b, GTP-binding protein B, GTBPB, SAR1B, SARA2, SARB
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图像 |
SAR1B antibody (Center) (Cat. AMM07712G) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the SAR1B antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
SAR1B Antibody (Center) (Cat. AMM07712G) western blot analysis in MCF-7,MDA-MB453 cell line lysates (35ug/lane).This demonstrates the SAR1B antibody detected the SAR1B protein (arrow).
SAR1B Antibody (Center) (Cat. AMM07712G) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
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说明书 |
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数量 |
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