全部产品分类
品牌 |
Leading Biology | 货号 |
APR11976G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality GABRG2 antibody (Center).
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分子量 |
54162 Da
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细胞定位 |
Antigen Cellular Localization:
Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein
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宿主 |
Rabbit
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种属反应性 |
Human, Mouse
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免疫原 |
198-224 aa
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靶点 |
This GABRG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 198-224 amino acids from the Central region of human GABRG2.
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亚型 |
Rabbit Ig
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基因ID |
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UniProt ID |
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功能 |
Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine. Functions as receptor for diazepines and various anesthetics, such as pentobarbital; these are bound at a separate allosteric effector binding site. Functions as ligand- gated chloride channel.
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总结 |
This gene encodes a gamma-aminobutyric acid (GABA)receptor. GABA is the major inhibitory neurotransmitter in themammlian brain, where it acts at GABA-A receptors, which areligand-gated chloride channels. GABA-A receptors are pentameric,consisting of proteins from several subunit classes: alpha, beta,gamma, delta and rho. Mutations in this gene have been associatedwith epilepsy and febrile seizures. Multiple transcript variantsencoding different isoforms have been identified for this gene.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC-P, E
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稀释方法 |
WB~~1:1000
IHC-P~~1:50~100
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别名 |
Gamma-aminobutyric acid receptor subunit gamma-2, GABA(A) receptor subunit gamma-2, GABRG2
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图像 |
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说明书 |
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数量 |
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