全部产品分类
品牌 |
Leading Biology | 货号 |
AMM07702G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Ryk (mouse) antibody (internal region).
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分子量 |
67507 Da
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细胞定位 |
Antigen Cellular Localization:
Membrane; Single-pass type I membrane protein. Nucleus. Cytoplasm. Note=In cells that have undergone neuronal differentiation, the C-terminal cleaved part is translocated from the cytoplasm to the nucleus.
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宿主 |
Goat
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亚型 |
IgG
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通用名 |
JTK5A
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基因ID |
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UniProt ID |
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功能 |
May be a coreceptor along with FZD8 of Wnt proteins, such as WNT1, WNT3, WNT3A and WNT5A. Involved in neuron differentiation, axon guidance, corpus callosum establishment and neurite outgrowth. In response to WNT3 stimulation, receptor C- terminal cleavage occurs in its transmembrane region and allows the C-terminal intracellular product to translocate from the cytoplasm to the nucleus where it plays a crucial role in neuronal development.
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总结 |
This antibody is expected to recognize both reported isoforms (NP_038677.3; NP_001036072.1).
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形式 |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
E
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别名 |
Tyrosine-protein kinase RYK, 2.7.10.1, RYK, JTK5A
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说明书 |
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数量 |
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