您好,欢迎光临安诺伦(北京)生物科技商城!
全国服务热线:400-965-8633
关注我们
  • 会员中心
  • 会员中心
    询价列表
    0

    最新加入的商品

    0 件商品 合计:¥ 0
  • 会员中心
    购物车

    最新加入的商品

    件商品 合计:¥ 0

全部产品分类

自主品牌
当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > Polyclonal Antibodies > NRP1 Antibody (C-term)

NRP1 Antibody (C-term)

货号 货期 规格 / 价格 询价
APR14083G 100 μl / ¥5450

NRP1 Antibody (C-term)

品牌

Leading Biology

货号

APR14083G

产品分类

Polyclonal Antibodies

研究领域

产品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality NRP1 antibody (C-term).

分子量

103134 Da

细胞定位

Antigen Cellular Localization: Cell membrane; Single-pass type I membrane protein

宿主

Rabbit

种属反应性

Human

免疫原

722-750 aa

靶点

This NRP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 722-750 amino acids from the C-terminal region of human NRP1.

亚型

Rabbit Ig

通用名

NRP, VEGF165R

基因ID

UniProt ID

功能

The membrane-bound isoform 1 is a receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. It mediates the chemorepulsant activity of semaphorins. It binds to semaphorin 3A, The PLGF-2 isoform of PGF, The VEGF-165 isoform of VEGF and VEGF-B. Coexpression with KDR results in increased VEGF-165 binding to KDR as well as increased chemotaxis. It may regulate VEGF-induced angiogenesis.

总结

NRP1 is a membrane-bound coreceptor to a tyrosine kinase receptor for both vascular endothelial growth factor (VEGF; MIM 192240) and semaphorin (see SEMA3A; MIM 603961) family members. NRP1 plays versatile roles in angiogenesis, axon guidance, cell survival, migration, and invasion.

形式

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

储存条件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

应用

WB, IHC-P, FC, E

稀释方法

WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50

别名

Neuropilin-1, Vascular endothelial cell growth factor 165 receptor, CD304, NRP1, NRP, VEGF165R

图像

Western blot analysis of NRP1 Antibody (C-term) (Cat. APR14083G) in MDA-MB435 cell line lysates (35ug/lane). NRP1 (arrow) was detected using the purified Pab.

Formalin-fixed and paraffin-embedded human skeletal muscle reacted with NRP1 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

NRP1 Antibody (C-term) (Cat. APR14083G) flow cytometric analysis of MDA-MB435 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

说明书

数量

相关产品

选择 品牌 货号 产品名称 规格 分类 研究领域 说明书 数量 目录价
1 Leading Biology APR05963G EGFR Antibody (Y1092) 100 μl Polyclonal Antibodies
¥4950.00 订购 询价
2 Leading Biology APR03116G BRCA1 Antibody (aa1847-1863) 100 μl Polyclonal Antibodies
¥4950.00 订购 询价
3 Leading Biology AMM05633G Bombesin Receptor 2 (extracellular) Antibody 50 μl Polyclonal Antibodies
¥6950.00 订购 询价
4 Leading Biology APR10986G AP3B1 Antibody (aa2-14) 50 μg Polyclonal Antibodies
¥4950.00 订购 询价
5 Leading Biology APR11512G Bestrophin-1 (extracellular) Antibody 50 μl Polyclonal Antibodies
¥6950.00 订购 询价
6 Leading Biology APG01407G A3 Adenosine Receptor Antibody 50 μl Polyclonal Antibodies
¥6950.00 订购 询价

产品添加成功!

购物车已有 0 件产品

加入询价单成功!

询价单已有 0 件产品