全部产品分类
品牌 |
Leading Biology | 货号 |
APR10891G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality LPIN2 antibody (Center).
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分子量 |
99399 Da
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细胞定位 |
Antigen Cellular Localization:
Nucleus. Cytoplasm, cytosol. Endoplasmic reticulum membrane Note=Translocates to endoplasmic reticulum membrane with increasing levels of oleate.
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
262-288 aa
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靶点 |
This LPIN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 262-288 amino acids from the Central region of human LPIN2.
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亚型 |
Rabbit Ig
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通用名 |
KIAA0249
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基因ID |
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UniProt ID |
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功能 |
Plays important roles in controlling the metabolism of fatty acids at differents levels. Acts as a magnesium-dependent phosphatidate phosphatase enzyme which catalyzes the conversion of phosphatidic acid to diacylglycerol during triglyceride, phosphatidylcholine and phosphatidylethanolamine biosynthesis in the reticulum endoplasmic membrane. Acts also as a nuclear transcriptional coactivator for PPARGC1A to modulate lipid metabolism (By similarity).
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总结 |
Defects in LPIN2 are the cause of Majeed syndrome. Majeed syndrome is an autosomal recessive disorder combining features of chronic recurrent multifocal osteomyelitis, congenital dyserythropoietic anemia and inflammatory dermatosis.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC-P, FC, E
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稀释方法 |
WB~~1:1000
IHC-P~~1:50~100
FC~~1:10~50
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别名 |
Phosphatidate phosphatase LPIN2, Lipin-2, LPIN2, KIAA0249
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图像 |
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说明书 |
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数量 |
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