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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > Polyclonal Antibodies > PRPS1/PRPS2/PRPS3 Antibody (N-term)

PRPS1/PRPS2/PRPS3 Antibody (N-term)

货号 货期 规格 / 价格 询价
APR10848G 100 μl / ¥5450

PRPS1/PRPS2/PRPS3 Antibody (N-term)

品牌

Leading Biology

货号

APR10848G

产品分类

Polyclonal Antibodies

研究领域

产品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PRPS1/PRPS2/PRPS3 antibody (N-term).

分子量

34834 Da

宿主

Rabbit

种属反应性

Human, Mouse

免疫原

79-109 aa

靶点

This PRPS1/PRPS2/PRPS3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 79-109 amino acids from the N-terminal region of human PRPS1/PRPS2/PRPS3.

亚型

Rabbit Ig

基因ID

UniProt ID

功能

Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis.

总结

Phosphoribosylpyrophosphate synthetase (PRPS; EC 2.7.6.1) catalyzes the phosphoribosylation of ribose 5-phosphate to 5-phosphoribosyl-1-pyrophosphate, which is necessary for the de novo and salvage pathways of purine, pyrimidine, and pyridine biosynthesis. By PCR of human lymphoblast mRNA using primers based on the cDNA sequence of rat PRS I (Prps1), Roessler et al. (1990) isolated a partial human PRPS1 cDNA. They used this partial cDNA to screen lymphoblast cDNA libraries and isolated additional cDNAs corresponding to the entire PRPS1 coding region. The deduced PRPS1 protein has 318 amino acids.

形式

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

储存条件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

应用

WB, E

稀释方法

WB~~1:1000

别名

Ribose-phosphate pyrophosphokinase 1, PPRibP, Phosphoribosyl pyrophosphate synthase I, PRS-I, PRPS1

图像

The anti-PRPS1/2/3 Pab (Cat. APR10848G) is used in Western blot to detect PRPS1/2/3 in mouse kidney tissue lysate (Lane 1) and Hela cell lysate (Lane 2).

Role of PPP during MSC transformation. (A) G6PD activity decreased during MSC transformation (& 8727;, P=0.0132; t test). Western blot confirms the down-regulation of G6PD and the up-regulation of PRPS at the late stages of transformation.

说明书

数量

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