全部产品分类
品牌 |
Leading Biology | 货号 |
AMM08673G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality RBPMS antibody (C-term).
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分子量 |
21802 Da
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细胞定位 |
Antigen Cellular Localization:
Nucleus. Cytoplasm
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
166-193 aa
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靶点 |
This RBPMS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 166-193 amino acids from the C-terminal region of human RBPMS.
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亚型 |
Rabbit Ig
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通用名 |
HERMES
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基因ID |
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UniProt ID |
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功能 |
Acts as a coactivator of transcriptional activity. Required to increase TGFB1/Smad-mediated transactivation. Acts through SMAD2, SMAD3 and SMAD4 to increase transcriptional activity. Increases phosphorylation of SMAD2 and SMAD3 on their C- terminal SSXS motif, possibly through recruitment of TGFBR1. Promotes the nuclear accumulation of SMAD2, SMAD3 and SMAD4 proteins. Binds to poly(A) RNA.
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总结 |
Acts as a coactivator of transcriptional activity. Required to increase TGFB1/Smad-mediated transactivation. Acts through SMAD2, SMAD3 and SMAD4 to increase transcriptional activity. Increases phosphorylation of SMAD2 and SMAD3 on their C-terminal SSXS motif, possibly through recruitment of TGFBR1. Promotes the nuclear accumulation of SMAD2, SMAD3 and SMAD4 proteins. Binds to poly(A) RNA.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:1000
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别名 |
RNA-binding protein with multiple splicing, RBP-MS, Heart and RRM expressed sequence, Hermes, RBPMS, HERMES
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图像 |
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说明书 |
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数量 |
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