全部产品分类
品牌 |
Leading Biology | 货号 |
AMM08633G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality IDAS antibody (N-term).
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分子量 |
41720 Da
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细胞定位 |
Antigen Cellular Localization:
Nucleus. Note=Excluded from the nucleolus.
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
20-46 aa
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靶点 |
This IDAS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 20-46 amino acids from the N-terminal region of human IDAS.
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亚型 |
Rabbit Ig
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通用名 |
IDAS, MCI, MCIN
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基因ID |
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UniProt ID |
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功能 |
Transcription regulator specifically required for multiciliate cell differentiation. Acts in a multiprotein complex containing E2F4 and E2F5 that binds and activates genes required for centriole biogenesis. Required for the deuterosome-mediated acentriolar pathway (PubMed:25048963). Plays a role in mitotic cell cycle progression by promoting cell cycle exit. Modulates GMNN activity by reducing its affinity for CDT1 (PubMed:21543332, PubMed:24064211).
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总结 |
Transcription regulator required for multiciliate cell differentiation. Acts by promoting transcription of genes required for multiciliate cell formation. Probably acts in a multiprotein complex By similarity. Plays a role in mitotic cell cycle progression by promoting cell cycle exit. Ref.1
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:1000
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别名 |
Multicilin, Multiciliate differentiation and DNA synthesis-associated cell cycle protein, Protein Idas, MCIDAS, IDAS, MCI, MCIN
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图像 |
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说明书 |
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数量 |
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