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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > Polyclonal Antibodies > UPK3B Antibody (Center)

UPK3B Antibody (Center)

货号 货期 规格 / 价格 询价
AMM08702G 100 μl / ¥5450

UPK3B Antibody (Center)

品牌

Leading Biology

货号

AMM08702G

产品分类

Polyclonal Antibodies

研究领域

产品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality UPK3B antibody (Center).

分子量

33882 Da

细胞定位

Antigen Cellular Localization: Cell membrane; Single-pass type I membrane protein. Note=Heterodimer formation with UPK1B is a prerequisite to exit out of the endoplasmic reticulum (ER).

宿主

Rabbit

种属反应性

Human

免疫原

192-219 aa

靶点

This UPK3B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 192-219 amino acids from the Central region of human UPK3B.

亚型

Rabbit Ig

基因ID

UniProt ID

功能

Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. It also contributes to the formation of urothelial glycocalyx which may play an important role in preventing bacterial adherence (By similarity).

总结

UPK3B is a minor component of the apical plaques ofmammalian urothelium that binds and dimerizes with uroplakin-1b(UPK1B; MIM 602380), one of the major conserved urothelium membraneproteins. The other major conserved integral membrane proteins ofurothelial plaques are UPK1A (MIM 611557), UPK2 (MIM 611558), andUPK3A (MIM 611559) (Deng et al., 2002 [PubMed 12446744]).[suppliedby OMIM].

形式

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

储存条件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

应用

WB, E

稀释方法

WB~~1:1000

别名

Uroplakin-3b, UP3b, Uroplakin IIIb, UPIIIb, p35, UPK3B

图像

UPK3B Antibody (Center) (Cat. AMM08702G) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the UPK3B antibody detected the UPK3B protein (arrow).

说明书

数量

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