全部产品分类
品牌 |
Leading Biology | 货号 |
APR10899G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality NMNAT2 antibody (N-term).
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分子量 |
34439 Da
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细胞定位 |
Antigen Cellular Localization:
Cytoplasm. Golgi apparatus
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
13-40 aa
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靶点 |
This NMNAT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 13-40 amino acids from the N-terminal region of human NMNAT2.
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亚型 |
Rabbit Ig
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通用名 |
C1orf15, KIAA0479
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基因ID |
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UniProt ID |
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功能 |
Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form; nicotinic acid mononucleotide (NaMN) as substrate but with a lower efficiency. Cannot use triazofurin monophosphate (TrMP) as substrate. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD(+). For the pyrophosphorolytic activity prefers NAD(+), NADH and NAAD as substrates and degrades nicotinic acid adenine dinucleotide phosphate (NHD) less effectively. Fails to cleave phosphorylated dinucleotides NADP(+), NADPH and NAADP(+).
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总结 |
This gene product belongs to the nicotinamidemononucleotide adenylyltransferase (NMNAT) enzyme family, membersof which catalyze an essential step in NAD (NADP) biosyntheticpathway. Unlike the other human family member, which is localizedto the nucleus, and is ubiquitously expressed; this enzyme iscytoplasmic, and is predominantly expressed in the brain. Twotranscript variants encoding different isoforms have been found forthis gene.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:1000
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别名 |
Nicotinamide mononucleotide adenylyltransferase 2, NMN adenylyltransferase 2, Nicotinate-nucleotide adenylyltransferase 2, NaMN adenylyltransferase 2, NMNAT2, C1orf15, KIAA0479
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图像 |
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说明书 |
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数量 |
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