全部产品分类
品牌 |
Leading Biology | 货号 |
APR14093G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality ATL1 antibody (C-term).
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分子量 |
63544 Da
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细胞定位 |
Antigen Cellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cell projection, axon
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
477-504 aa
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靶点 |
This ATL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 477-504 amino acids from the C-terminal region of human ATL1.
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亚型 |
Rabbit Ig
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通用名 |
GBP3, SPG3A
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基因ID |
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UniProt ID |
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功能 |
GTPase tethering membranes through formation of trans- homooligomers and mediating homotypic fusion of endoplasmic reticulum membranes. Functions in endoplasmic reticulum tubular network biogenesis. May also regulate Golgi biogenesis. May regulate axonal development.
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总结 |
The protein encoded by this gene is a GTPase and a Golgibody transmembrane protein. The encoded protein can form ahomotetramer and has been shown to interact with spastin and withmitogen-activated protein kinase kinase kinase kinase 4. Thisprotein may be involved in axonal maintenance as evidenced by thefact that defects in this gene are a cause of spastic paraplegiatype 3. Three transcript variants encoding two different isoformshave been found for this gene.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:1000
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别名 |
Atlastin-1, 365-, Brain-specific GTP-binding protein, GTP-binding protein 3, GBP-3, hGBP3, Guanine nucleotide-binding protein 3, Spastic paraplegia 3 protein A, ATL1, GBP3, SPG3A
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图像 |
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说明书 |
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数量 |
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