品牌 |
Leading Biology | 货号 |
AMM08596G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality AKAP4 antibody (N-term).
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分子量 |
94477 Da
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细胞定位 |
Antigen Cellular Localization:
Cell projection, cilium, flagellum. Note=Localizes to the principle piece of the sperm flagellum
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
10-36 aa
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靶点 |
This AKAP4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 10-36 amino acids from the N-terminal region of human AKAP4.
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亚型 |
Rabbit Ig
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通用名 |
AKAP82
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基因ID |
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UniProt ID |
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功能 |
Major structural component of sperm fibrous sheath. Plays a role in sperm motility.
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总结 |
The A-kinase anchor proteins (AKAPs) are a group ofstructurally diverse proteins, which have the common function ofbinding to the regulatory subunit of protein kinase A (PKA) andconfining the holoenzyme to discrete locations within the cell.This gene encodes a member of the AKAP family. The encoded proteinis localized to the sperm flagellum and may be involved in theregulation of sperm motility. Alternative splicing of this generesults in two transcript variants encoding different isoforms.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC-P, E
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稀释方法 |
WB~~1:1000
IHC-P~~1:10~50
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别名 |
A-kinase anchor protein 4, AKAP-4, A-kinase anchor protein 82 kDa, AKAP 82, hAKAP82, Major sperm fibrous sheath protein, HI, Protein kinase A-anchoring protein 4, PRKA4, AKAP4 (HGNC:374), AKAP82
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图像 |
AKAP4 Antibody (N-term) (Cat. AMM08596G) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the AKAP4 antibody detected the AKAP4 protein (arrow).
AKAP4 Antibody (N-term) (AMM08596G)immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of AKAP4 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
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说明书 |
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数量 |
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