全部产品分类
品牌 |
Leading Biology | 货号 |
APR14251G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SLC12A6 antibody (N-term).
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分子量 |
127617 Da
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细胞定位 |
Antigen Cellular Localization:
Basolateral cell membrane; Multi-pass membrane protein
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
13-42 aa
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靶点 |
This SLC12A6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 13-42 amino acids from the N-terminal region of human SLC12A6.
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亚型 |
Rabbit Ig
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通用名 |
KCC3
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基因ID |
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UniProt ID |
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功能 |
Mediates electroneutral potassium-chloride cotransport. May be activated by cell swelling. May contribute to cell volume homeostasis in single cells.
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总结 |
This gene is a member of the K-Cl cotransporter (KCC)family. K-Cl cotransporters are integral membrane proteins thatlower intracellular chloride concentrations below theelectrochemical equilibrium potential. The proteins encoded by thisgene are activated by cell swelling induced by hypotonicconditions. Alternate splicing results in multiple transcriptvariants encoding different isoforms. Mutations in this gene areassociated with agenesis of the corpus callosum with peripheralneuropathy.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC-P, E
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稀释方法 |
WB~~1:1000
IHC-P~~1:10~50
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别名 |
Solute carrier family 12 member 6, Electroneutral potassium-chloride cotransporter 3, K-Cl cotransporter 3, SLC12A6, KCC3
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图像 |
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说明书 |
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数量 |
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