全部产品分类
品牌 |
Leading Biology | 货号 |
AMM08682G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SEC13 antibody (Center).
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分子量 |
35541 Da
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细胞定位 |
Antigen Cellular Localization:
Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus, nuclear pore complex. Note=In interphase, localizes at both sides of the NPC
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
72-100 aa
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靶点 |
This SEC13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 72-100 amino acids from the Central region of human SEC13.
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亚型 |
Rabbit Ig
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通用名 |
D3S1231E, SEC13L1, SEC13R
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基因ID |
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UniProt ID |
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功能 |
Functions as a component of the nuclear pore complex (NPC) and the COPII coat. At the endoplasmic reticulum, SEC13 is involved in the biogenesis of COPII-coated vesicles. As a component of the GATOR2 complex, inhibits GATOR1 complex, an inhibitor of the amino acid-sensing branch of the TORC1 pathway.
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总结 |
The protein encoded by this gene belongs to the SEC13family of WD-repeat proteins. It is a constituent of theendoplasmic reticulum and the nuclear pore complex. It hassimilarity to the yeast SEC13 protein, which is required forvesicle biogenesis from endoplasmic reticulum during the transportof proteins. Multiple alternatively spliced transcript variantshave been found.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, FC, E
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稀释方法 |
WB~~1:1000
FC~~1:10~50
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别名 |
Protein SEC13 homolog, SEC13-like protein 1, SEC13-related protein, SEC13, D3S1231E, SEC13L1, SEC13R
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图像 |
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说明书 |
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数量 |
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