全部产品分类
品牌 |
Leading Biology | 货号 |
APR06929G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SUSD3 Antibody.
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分子量 |
Predicted: 16, 22, 23, 28 kDa Observed: 23 kDa
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细胞定位 |
Antigen Cellular Localization:
Membrane; Single-pass membrane protein
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宿主 |
Rabbit
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种属反应性 |
Human, Mouse
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靶点 |
SUSD3; SUSD3 antibody is human and mouse reactive. Multiple isoforms of SUSD3 are known to exist.
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亚型 |
IgG
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基因ID |
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UniProt ID |
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总结 |
Little is known of the function of the sushi domain containing 3 protein (SUSD3), but its expression has been reported in estrogen receptor-alpha (ERalpha)-positive breast tumors with decreased expression reported in aggressive malignant tumors (1,2). Recently, SUSD3 has been found to promote estrogen-dependent cell proliferation and may regulate cell-cell and cell-substrate interactions and migration in breast cancer (3). Furthermore, elevated SUSD3 mRNA levels were observed in aromatase inhibitor-responsive breast tumors, suggesting that it may also serve as a novel predictor of response to endocrine therapy and a potential therapeutic target (3).
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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图像 |
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说明书 |
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数量 |
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