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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > Polyclonal Antibodies > RNF121 Antibody

RNF121 Antibody

货号 货期 规格 / 价格 询价
APR06922G 0.1 mg / ¥6950

RNF121 Antibody

品牌

Leading Biology

货号

APR06922G

产品分类

Polyclonal Antibodies

研究领域

产品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality RNF121 Antibody.

分子量

Predicted: 24, 27, 36 kDa Observed: 28 kDa

细胞定位

Antigen Cellular Localization: Membrane; Multi-pass membrane protein

宿主

Rabbit

种属反应性

Human, Mouse, Rat

靶点

RNF121; RNF121 antibody is human, mouse and rat reactive. Multiple isoforms of RNF121 are known to exist.

亚型

IgG

基因ID

UniProt ID

总结

RNF121 is an evolutionarily conserved E3 ligase ring finger protein that is expressed in the endoplasmic reticulum (1). It acts downstream of the unfolded protein response regulator protein kinase-like endoplasmic reticulum kinase (PERK). Overexpression of RNF121 during the early stages of gonad development led to aberrations in germline development and gonad migration, suggesting that it plays a role in endoplasmic reticulum-associated degradation machinery (1).

储存条件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

应用

WB, ICC, E

图像

Western blot analysis of RNF121 in MCF7 cell lysate with RNF121 antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide.

Immunocytochemistry of RNF121 in MCF7 cells with RNF121 antibody at 10 μg/ml.

说明书

数量

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