全部产品分类
品牌 |
Leading Biology | 货号 |
APR06916G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality KIR2DS2 Antibody.
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分子量 |
Predicted: 28, 33, 37 kDa Observed: 34, 42 kDa
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细胞定位 |
Antigen Cellular Localization:
Cell membrane; Single-pass type I membrane protein
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宿主 |
Rabbit
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种属反应性 |
Human
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靶点 |
KIR2DS2; KIR2DS2 antibody is human specific. Multiple isoforms are known to exist.
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亚型 |
IgG
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通用名 |
CD158J, NKAT5
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基因ID |
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UniProt ID |
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功能 |
Receptor on natural killer (NK) cells for HLA-C alleles. Does not inhibit the activity of NK cells.
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总结 |
Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells (1). The KIR proteins are classified by the number of extracellular immunoglobulin domains and by whether they have a long (L) or short (S) cytoplasmic domain (2,3). KIR proteins are thought to play an important role in regulation of the immune response (3). KIR2DS2 downregulates the cytotoxicity of NK cells upon recognition of specific class I major histocompatibility complex (MHC) molecules on target cells and is a receptor on natural killer (NK) cells for HLA-C alleles (3,4).
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IF, E
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图像 |
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说明书 |
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数量 |
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