全部产品分类
品牌 |
Leading Biology | 货号 |
APR06869G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SPINSTER Antibody.
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分子量 |
Predicted: 58 kDa Observed: 70 kDa
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细胞定位 |
Antigen Cellular Localization:
Mitochondrion inner membrane; Multi-pass membrane protein. Note=Colocalizes with SDHB
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宿主 |
Rabbit
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种属反应性 |
Human
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靶点 |
SPNS1; SPINSTER antibody is human specific. At least four isoforms of SPINSTER are known to exist. This antibody is predicted to not cross-react with other members of the spinster family of proteins.
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亚型 |
IgG
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通用名 |
SPIN1
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基因ID |
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UniProt ID |
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功能 |
Sphingolipid transporter (By similarity). May be involved in necrotic or autophagic cell death.
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总结 |
SPINSTER, also known as SPNS1 or SPIN1, is a 528 amino acid multi-pass membrane protein that localizes to the inner mitochondrial membrane and belongs to the spinster subfamily of the major facilitator superfamily (1). SPINSTER interacts with Bcl-x and Bcl-2 and, via this interaction, is thought to be involved in necrotic or autophagic cell death (2). The related protein SPNS2 is critical for the normal lymphocyte localization and mammalian immune system function (1,3).
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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图像 |
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说明书 |
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数量 |
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