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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > Polyclonal Antibodies > TMIGD2 Antibody

TMIGD2 Antibody

货号 货期 规格 / 价格 询价
APR06861G 0.1 mg / ¥6950

TMIGD2 Antibody

品牌

Leading Biology

货号

APR06861G

产品分类

Polyclonal Antibodies

研究领域

产品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TMIGD2 Antibody.

分子量

Predicted: 31 kDa Observed: 26 kDa

细胞定位

Antigen Cellular Localization: Cell membrane; Single-pass type I membrane protein

宿主

Rabbit

种属反应性

Human, Mouse

靶点

TMIGD2; TMIGD2 antibody is human and mouse reactive. At least three isoforms of TMIGD2 are known to exist; this antibody will detect all three. TMIGD2 antibody is predicted to not cross-react with TMIGD1.

亚型

IgG

通用名

CD28H, IGPR1

基因ID

UniProt ID

功能

Plays a role in cell-cell interaction, cell migration, and angiogenesis. Through interaction with HHLA2, costimulates T- cells in the context of TCR-mediated activation. Enhances T-cell proliferation and cytokine production via an AKT-dependent signaling cascade.

总结

TMIGD2 (transmembrane and immunoglobulin domain containing 1), also known as immunoglobulin-containing and proline-rich receptor 1 (IGPR1), is novel adhesion molecule that is expressed in multiple tissues, primarily in cells of epithelium and endothelium origins (1). TMIGD2 is thought to be involved in angiogenesis and regulates cellular morphology, homophilic cell aggregation, and cell-cell interaction. TMIGD2 activity also modulates actin stress fiber formation and focal adhesion and reduces cell migration (1).

储存条件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

应用

WB, IHC-P, E

图像

Western blot analysis of TMIGD2 in mouse small intestine tissue lysate with TMIGD2 antibody at 1 μg/ml.

Immunohistochemistry of TMIGD2 in human small intestine tissue with TMIGD2 antibody at 5 μg/mL.

说明书

数量

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