品牌 |
Leading Biology | 货号 |
APR06813G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality ERRF Antibody.
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分子量 |
Predicted: 19 kDa Observed: 15 kDa
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宿主 |
Rabbit
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种属反应性 |
Human, Mouse
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靶点 |
C1orf64;
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亚型 |
IgG
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基因ID |
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UniProt ID |
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总结 |
ERRF Antibody: The estrogen receptor-related factor (ERRF) is a recently identified protein whose expression is upregulated in multiple cell lines and primary breast cancer tumors. Increased ERRF expression was significantly associated with ER or progesterone receptor (PR) positivity even in HER2-negative tumors. This higher ERRF expression correlated with better disease-free survival and overall survival. In two ER-positive breast cancer cell lines, knockdown of ERRF suppressed cell growth in vitro and tumorigenesis in xenograft models, suggesting that ERRF plays a role in estrogen-ER-mediated breast cancer cell growth and may thus be a potential therapeutic target.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC-P, IF, E
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图像 |
Western blot analysis of ERRF in HeLa cell lysate with ERRF antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.
Immunocytochemistry of ERRF in HeLa cells with ERRF antibody at 2.5 μg/ml.
Immunofluorescence of ERRF in HeLa cells with ERRF antibody at 20 μg/ml. |
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说明书 |
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数量 |
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