全部产品分类
品牌 |
Leading Biology | 货号 |
APR06725G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality RILPL1 Antibody.
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分子量 |
47108 Da
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细胞定位 |
Antigen Cellular Localization:
Cytoplasm, cytosol. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cell projection, cilium
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宿主 |
Rabbit
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种属反应性 |
Human, Mouse, Rat
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靶点 |
RILPL1; At least three isoforms of RILPL1 are known to exist; this antibody will detect the two shorter isoforms. RILPL1 antibody is predicted to not cross-react with RILP.
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亚型 |
IgG
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通用名 |
RLP1
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基因ID |
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UniProt ID |
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功能 |
Plays a role in the regulation of cell shape and polarity. Plays a role in cellular protein transport, including protein transport away from primary cilia. Neuroprotective protein, which acts by sequestring GAPDH in the cytosol and prevent the apoptotic function of GAPDH in the nucleus. Competes with SIAH1 for binding GAPDH (By similarity). Does not regulate lysosomal morphology and distribution.
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总结 |
RILPL1 Antibody: While the function of the Rab interacting lysosomal protein-like 1 (RILPL1) remains unknown, the homologous protein RILP is a small GTPase that controls transport to endocytic compartments, suggesting RILPL1 may have similar functions. However, overexpression of RILP caused enlarged lysosomes that are more centrally located in the cell, while overexpression of RILPL1 had no visible effect on the location or morphology of lysosomes.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IF, E
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图像 |
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说明书 |
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数量 |
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