全部产品分类
品牌 |
Leading Biology | 货号 |
APR06685G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality REQUIEM Antibody.
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分子量 |
44155 Da
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细胞定位 |
Antigen Cellular Localization:
Nucleus. Cytoplasm. Note=30% nuclear. 70% cytoplasmic
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宿主 |
Rabbit
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种属反应性 |
Human, Mouse
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靶点 |
DPF2; Requiem antibody is predicted to not cross-react with other DPF protein family members.
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亚型 |
IgG
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通用名 |
BAF45D, REQ, UBID4
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基因ID |
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UniProt ID |
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功能 |
May be a transcription factor required for the apoptosis response following survival factor withdrawal from myeloid cells. Might also have a role in the development and maturation of lymphoid cells.
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总结 |
REQUIEM Antibody: Requiem is a member of the d4 domain family, characterized by a zinc finger-like structural motif. This protein functions as a transcription factor which is necessary for the apoptotic response following deprivation of survival factors. It is expressed in numerous tissues in both cytosolic and nuclear regions and likely serves a regulatory role in rapid hematopoietic cell growth and turnover. Requiem has been found to act as an adaptor protein that links the NF-κB and SWI/SNF chromatin remodeling factor and is considered a candidate gene for multiple endocrine neoplasia type I, an inherited cancer syndrome involving multiple parathyroid, enteropancreatic, and pituitary tumors.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC-P, IF, E
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图像 |
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说明书 |
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数量 |
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