全部产品分类
品牌 |
Leading Biology | 货号 |
APR06683G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality PEAR1 Antibody.
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分子量 |
110666 Da
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细胞定位 |
Antigen Cellular Localization:
Cell membrane; Single-pass membrane protein. Note=Detected on the cell surface in resting platelets.
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宿主 |
Rabbit
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种属反应性 |
Human, Mouse, Rat
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靶点 |
PEAR1;
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亚型 |
IgG
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通用名 |
MEGF12
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基因ID |
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UniProt ID |
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功能 |
When overexpressed, reduces the number of both early and late non-adherent myeloid progenitor cells.
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总结 |
PEAR1 Antibody: Platelet endothelial aggregation receptor 1 (PEAR1) is a platelet receptor that signals upon the formation of platelet-platelet contacts independent of platelet activation and secondary to platelet aggregation. Upon platelet aggregation stimulated by physiological agonists, PEAR1 becomes tyrosine- and serine-phosphorylated; the tyrosine phosphorylation can be inhibited by eptifibatide, an aIIbbeta3 antagonist that also inhibits platelet aggregation. Recent studies have indicated that genetic variations in PEAR1, may be associated with enhanced agonist-induced platelet aggregation.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC-P, IF, E
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图像 |
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说明书 |
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数量 |
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