全部产品分类
品牌 |
Leading Biology | 货号 |
APR06649G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SCUBE1 Antibody.
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分子量 |
107910 Da
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细胞定位 |
Antigen Cellular Localization:
Secreted. Cell membrane; Peripheral membrane protein
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宿主 |
Rabbit
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种属反应性 |
Human
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靶点 |
SCUBE1;
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亚型 |
IgG
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基因ID |
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UniProt ID |
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功能 |
Could function as an adhesive molecule and its matrix bound and soluble fragments may play a critical role in vascular biology.
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总结 |
SCUBE1 Antibody: SCUBE1 is an EGF-related protein with a CUB (C1s-like) domain that is expressed primarily in the developing gonad, nervous system, somites, surface ectoderm and limb buds. The N-terminal EGF-like repeats of SCUBE1 participate in the formation of adhesions in a Ca2+-dependent fashion. In contrast, the C-terminal cysteine-rich motifs and CUB domain can directly bind and antagonize bone morphogenic protein activity; genetic ablation of this region resulted in brain malformation in mice embryos, suggesting SCUBE1 plays a role in brain morphogenesis. SCUBE1 has also been implicated in early craniofacial development in mice.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IF, ICC, E
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图像 |
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说明书 |
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数量 |
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