全部产品分类
品牌 |
Leading Biology | 货号 |
APC00025G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality TCC52 Antibody.
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分子量 |
50517 Da
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细胞定位 |
Antigen Cellular Localization:
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome
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宿主 |
Chicken
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种属反应性 |
Human, Mouse, Rat
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靶点 |
DCAF12;
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亚型 |
IgY
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通用名 |
KIAA1892, TCC52, WDR40A
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基因ID |
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UniProt ID |
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功能 |
May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.
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总结 |
TCC52 Antibody: Cancer-testis (CT) antigens are a type of antigen whose expression is highly restricted, primarily in normal testis, but aberrantly in different tumor types. Their immunogenicity in cancer patients makes them prime targets for immunotherapy of human tumors. One such CT antigen is TCC52, a novel centrosomal protein. TCC52 is a WD repeat-containing protein that interacts with the COP9 signalosome, a macromolecular complex that interacts with cullin-RING E3 ligases and regulates their activity by hydrolyzing cullin-Nedd8 conjugates. The normal biological function of this protein is not known at this time.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, ICC, E
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图像 |
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说明书 |
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数量 |
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