品牌 |
Leading Biology | 货号 |
APR06609G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CAZIP Antibody.
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分子量 |
150195 Da
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细胞定位 |
Antigen Cellular Localization:
Cytoplasm, cytoskeleton. Note=Associated with the microtubule network at the growing distal tip (the plus-end) of microtubules
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宿主 |
Rabbit
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种属反应性 |
Human, Mouse
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靶点 |
MTUS2;
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亚型 |
IgG
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通用名 |
CAZIP, KIAA0774, TIP150
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基因ID |
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UniProt ID |
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功能 |
Binds microtubules. Together with MAPRE1 may target the microtubule depolymerase KIF2C to the plus-end of microtubules. May regulate the dynamics of microtubules at their growing distal tip.
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总结 |
CAZIP Antibody: CAZIP, also known as TIP150, contains a leucine-zipper domain at the C-terminus and has at least three isoforms. CAZIP is expressed in heart during early cardiac development and in parts of the nervous system in later embryonic development. It is thought to bind microtubules and facilitate the end-binding protein 1 (EB1)-dependent loading of MCAK onto microtubules plus ends and orchestrates the dynamics at the plus end of microtubules. CAZIP may regulate the dynamics of microtubules at their growing distal tip.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC-P, IF, E
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图像 |
Western blot analysis of CAZIP in A20 cell lysate with CAZIP antibody at (A) 0.5 and (B) 1 μg/mL.
Immunohistochemistry of CAZIP in mouse heart tissue with CAZIP antibody at 5 μg/mL.
Immunofluorescence of CAZIP in mouse heart tissue with CAZIP antibody at 20 μg/mL. |
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说明书 |
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数量 |
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