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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > Polyclonal Antibodies > Neuregulin-1 Type III (extracellular) Antibody

Neuregulin-1 Type III (extracellular) Antibody

货号 货期 规格 / 价格 询价
APR00523G 50 μl / ¥6950

Neuregulin-1 Type III (extracellular) Antibody

品牌

Leading Biology

货号

APR00523G

产品分类

Polyclonal Antibodies

研究领域

产品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Neuregulin-1 Type III (extracellular) Antibody.

分子量

70392 Da

宿主

Rabbit

种属反应性

Human, Mouse

基因ID

UniProt ID

总结

Direct ligand for ERBB3 and ERBB4 tyrosine kinase receptors. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. The multiple isoforms perform diverse functions such as inducing growth and differentiation of epithelial, glial, neuronal, and skeletal muscle cells; inducing expression of acetylcholine receptor in synaptic vesicles during the formation of the neuromuscular junction; stimulating lobuloalveolar budding and milk production in the mammary gland and inducing differentiation of mammary tumor cells; stimulating Schwann cell proliferation; implication in the development of the myocardium such as trabeculation of the developing heart. Isoform 10 may play a role in motor and sensory neuron development.

形式

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

储存条件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

应用

WB

图像

Western blot analysis of rat dorsal root ganglion lysate:1.Anti-Neuregulin-1 Type III (extracellular) antibody (APR00523G), (1:200).2. Anti-Neuregulin-1 Type III (extracellular) antibody, preincubated with the control peptide antigen.

Western blot analysis of rat brain membranes (lanes 1 and 3) and mouse brain membranes (lanes 2 and 4):1,2.Anti-Neuregulin-1 type III (extracellular) antibody (APR00523G), (1:200).3,4. Anti-Neuregulin-1 Type III (extracellular) antibody, preincubated with the control peptide antigen.

说明书

数量

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