全部产品分类
品牌 |
Leading Biology | 货号 |
APR00515G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality KCa1.1 (1184-1200) Antibody.
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分子量 |
134396 Da
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宿主 |
Rabbit
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种属反应性 |
Human, Mouse, Rat
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靶点 |
Peptide (C)STANRPNRPKSRESRDK, corresponding to amino acid residues 1184-1200 of mouse KCa1.1??(Accession number Q08460). Intracellular, C-terminal part.
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基因ID |
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UniProt ID |
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总结 |
KCa1.1 (BKCa, Maxi K+ or slo) is part of a structurally diverse group of K+ channels that are activated by an increase in intracellular Ca2+. KCa1.1 shows a large single channel conductance when recordedelectrophysiologically and hence its name. It differs from the rest of the subfamily members in that it can be activated by both an increase in intracellular Ca2+ and by membrane depolarization. KCa1.1 is expressed in virtually all cell types where it causes hyperpolarization and helps to connectbetween intracellular Ca2+ signaling pathways and membrane excitability. Indeed, KCa1.1 channels have a crucial role in smooth muscle contractility, neuronal spike shaping andneurotransmitter release.
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形式 |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IP
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稀释方法 |
WB~~1:200-1:2000
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图像 |
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说明书 |
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数量 |
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