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> 抗原抗体、ELISA、WB > 一抗 > Monoclonal Antibodies > Functional TRAIL-R1 (human) Antibody, mAb(preservative free)品牌 |
Leading Biology | 货号 |
AMP00001G |
产品分类 |
Monoclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Functional TRAIL-R1 (human) Antibody, mAb(preservative free).
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分子量 |
50089 Da
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细胞定位 |
Antigen Cellular Localization:
Membrane; Single-pass type I membrane protein
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宿主 |
Purified From Concentrated Hybridoma Tissue Culture Supernatant.
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种属反应性 |
Human
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靶点 |
Recognizes human TRAIL-R1. Does not cross-react with human TRAIL-R2, -R3 or -R4.
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克隆号 |
HS101
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亚型 |
Mouse IgG1
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通用名 |
APO2, DR4, TRAILR1
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基因ID |
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UniProt ID |
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功能 |
Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF- kappa-B.
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总结 |
TRAIL-R1 is a receptor for the cytotoxic ligand TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa.
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形式 |
Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
FC, ICC, IP
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说明书 |
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数量 |
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