全部产品分类
品牌 |
Leading Biology | 货号 |
AMP00003G |
产品分类 |
Monoclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Functional LAG-3 Antibody, mAb (blocking).
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分子量 |
57449 Da
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细胞定位 |
Antigen Cellular Localization:
Membrane; Single-pass type I membrane protein
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宿主 |
Purified From Concentrated Hybridoma Tissue Culture Supernatant.
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种属反应性 |
Human, Monkey
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靶点 |
Recognizes human and monkey LAG-3.
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克隆号 |
1.10E+04
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亚型 |
Mouse IgG1
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通用名 |
FDC
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基因ID |
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UniProt ID |
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功能 |
Involved in lymphocyte activation. Binds to HLA class-II antigens.
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总结 |
Lymphocyte activation gene 3 (LAG-3; CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell co-receptor CD4 and binds to MHC class II molecules but with a significantly higher affinity than CD4.
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形式 |
Liquid. In PBS containing 0.02% sodium azide.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC, ICC, E, IP
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说明书 |
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数量 |
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