全部产品分类
品牌 |
Leading Biology | 货号 |
APS00009G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality VWF / Von Willebrand Factor Antibody (FITC).
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分子量 |
309kDa
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细胞定位 |
Antigen Cellular Localization:
Secreted. Secreted, extracellular space, extracellular matrix. Note=Localized to storage granules
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宿主 |
Sheep
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种属反应性 |
Human
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靶点 |
Recognizes human Von Willebrand Factor (vWF). No arcs when tested by IEP against human serum. Identity has been confirmed by double diffusion (Ouchterlony) vs. human vWF and an anti-human vWF of known specificity.
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通用名 |
F8VWF
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基因ID |
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UniProt ID |
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功能 |
Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex GPIb-IX-V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma.
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总结 |
Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex GPIb-IX-V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
IHC-P, IF, IHC-Fr
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稀释方法 |
IF (1:25-1:50), IHC-P (1:200),
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图像 |
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说明书 |
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数量 |
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