全部产品分类
品牌 |
Leading Biology | 货号 |
APR00891G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SH3RF1 antibody - middle region.
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分子量 |
93kDa
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细胞定位 |
Antigen Cellular Localization:
Cytoplasm, perinuclear region. Cell projection, lamellipodium. Cytoplasm. Golgi apparatus, trans- Golgi network. Note=Colocalizes, with AKT2, in lamellipodia (By similarity). Colocalizes, with HERP1, in trans-Golgi network
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宿主 |
Rabbit
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种属反应性 |
Human, Mouse, Rat, Rabbit, Horse, Bovine, Guinea Pig, Dog
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通用名 |
KIAA1494, POSH, RNF142, SH3MD2
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基因ID |
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UniProt ID |
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功能 |
Acts as a scaffold protein, contributes to Rac-induced signal transduction such as JNKs (MAPK8 and MAPK9) activation and induces apoptosis. Within a signaling complex, it probably recruits protein kinases such as MAP3K10 or MAP3K11 which are in turn activated leading to the sequential activation of MAP2K4, MAP2K7 and JNKs (MAPK8 and MAPK9) (By similarity). May be involved in targeting of HIV-1 GAG and GAG-POL polyproteins to the plasma membrane. Plays an essential role in the targeting of HIV-1 Gag to the plasma membrane, this function is dependent on it's RING domain, and hence it's E3 ligase activity.
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形式 |
Liquid
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB
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图像 |
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说明书 |
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数量 |
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