品牌 |
Leading Biology | 货号 |
APR00874G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality RBBP6 antibody - N-terminal region.
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分子量 |
201kDa
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细胞定位 |
Antigen Cellular Localization:
Nucleus, nucleolus. Chromosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome Note=Colocalizes with mitotic chromosomes. Colocalizes with NEK6 in the centrosome
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宿主 |
Rabbit
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种属反应性 |
Human, Mouse, Rat, Rabbit, Pig, Bovine, Dog
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通用名 |
P2PR, PACT, RBQ1
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基因ID |
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UniProt ID |
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功能 |
E3 ubiquitin-protein ligase which promotes ubiquitination of YBX1, leading to its degradation by the proteasome. May play a role as a scaffold protein to promote the assembly of the p53/TP53-MDM2 complex, resulting in increase of MDM2-mediated ubiquitination and degradation of p53/TP53; may function as negative regulator of p53/TP53, leading to both apoptosis and cell growth.
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形式 |
Liquid
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB
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图像 |
WB Suggested Anti-RBBP6 Antibody Titration: 0.2-1 μg/ml Positive Control: NCI-H226 cell lysate |
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说明书 |
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数量 |
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