全部产品分类
品牌 |
Leading Biology | 货号 |
APR00843G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality PLUNC antibody - middle region.
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分子量 |
28kDa
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细胞定位 |
Antigen Cellular Localization:
Secreted. Note=Apical side of airway epithelial cells. Detected in airway surface liquid, nasal mucus and sputum
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宿主 |
Rabbit
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种属反应性 |
Human, Mouse, Rat, Rabbit, Pig, Goat, Bovine, Guinea Pig, Dog
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通用名 |
LUNX, NASG, PLUNC, SPLUNC1, SPURT
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基因ID |
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UniProt ID |
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功能 |
Plays a role in the innate immune responses of the upper airways. Reduces the surface tension in secretions from airway epithelia and inhibits the formation of biofilm by pathogenic Gram-negative bacteria, such as P.aeruginosa and K.pneumoniae. Binds bacterial lipopolysaccharide (LPS). Negatively regulates proteolytic cleavage of SCNN1G, an event that is required for activation of the epithelial sodium channel (ENaC), and thereby contributes to airway surface liquid homeostasis and proper clearance of mucus. Plays a role in the airway inflammatory response after exposure to irritants. May attract macrophages and neutrophils. May be associated with tumor progression.
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形式 |
Liquid
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC
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图像 |
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说明书 |
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数量 |
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