品牌 |
Leading Biology | 货号 |
APR00789G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality RBM38 antibody - N-terminal region.
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分子量 |
26kDa
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细胞定位 |
Antigen Cellular Localization:
Cytoplasm, cytosol. Nucleus
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宿主 |
Rabbit
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种属反应性 |
Human, Mouse, Rat, Zebrafish, Pig, Bovine, Dog
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通用名 |
RNPC1, SEB4
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基因ID |
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UniProt ID |
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功能 |
RNA-binding protein that specifically bind the 3'-UTR of CDKN1A transcripts, leading to maintain the stability of CDKN1A transcripts, thereby acting as a mediator of the p53/TP53 family to regulate CDKN1A. CDKN1A is a cyclin-dependent kinase inhibitor transcriptionally regulated by the p53/TP53 family to induce cell cycle arrest. Isoform 1, but not isoform 2, has the ability to induce cell cycle arrest in G1 and maintain the stability of CDKN1A transcripts induced by p53/TP53. Also acts as a mRNA splicing factor. Specifically regulates the expression of FGFR2- IIIb, an epithelial cell-specific isoform of FGFR2. Plays a role in myogenic differentiation.
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形式 |
Liquid
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC
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图像 |
Rabbit Anti-RBM38 Antibody Paraffin Embedded Tissue: Human Kidney Cellular Data: Epithelial cells of renal tubule Antibody Concentration: 4.0-8.0 μg/ml Magnification: 400X
WB Suggested Anti-RBM38 Antibody Titration: 0.2-1 μg/ml Positive Control: RPMI 8226 cell lysateRBM38 is supported by BioGPS gene expression data to be expressed in RPMI 8226 |
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说明书 |
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数量 |
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