全部产品分类
品牌 |
Leading Biology | 货号 |
APR00726G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality BLOC1S1 Antibody - N-terminal region.
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分子量 |
16kDa
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细胞定位 |
Antigen Cellular Localization:
Mitochondrion intermembrane space. Mitochondrion matrix. Cytoplasm, cytosol
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宿主 |
Rabbit
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种属反应性 |
Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Horse, Bovine, Dog
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通用名 |
BLOS1, GCN5L1, RT14
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基因ID |
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UniProt ID |
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功能 |
Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May negatively regulate aerobic respiration through mitochondrial protein lysine-acetylation. May counteract the action of the deacetylase SIRT3 by acetylating and regulating proteins of the mitochondrial respiratory chain including ATP5A1 and NDUFA9.
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形式 |
Liquid
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB
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图像 |
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说明书 |
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数量 |
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