品牌 |
Leading Biology | 货号 |
APR00666G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Uhrf2 antibody - N-terminal region.
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分子量 |
90kDa
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细胞定位 |
Antigen Cellular Localization:
Nucleus {ECO:0000255|PROSITE- ProRule:PRU00358, ECO:0000269|PubMed:21598301}. Note=Enriched at pericentric heterochromatin (PH). This localization is dependent on the interaction with H3K9me3
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宿主 |
Rabbit
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种属反应性 |
Human, Mouse, Rat, Rabbit, Pig, Goat, Horse, Bovine, Dog
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通用名 |
Nirf
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基因ID |
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UniProt ID |
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功能 |
E3 SUMO-, but not ubiquitin-, protein ligase for ZNF131 (By similarity). E3 ubiquitin-protein ligase that is an intermolecular hub protein in the cell cycle network. Ubiquitinates cyclins, CCND1 and CCNE1, in an apparently phosphorylation-independent manner and induces G1 arrest. Also ubiquitinates PCNP leading to its degradation by the proteasome. Through cooperative DNA and histone binding, may contribute to a tighter epigenetic control of gene expression in differentiated cells.
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形式 |
Liquid
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB
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图像 |
WB Suggested Anti-Uhrf2 Antibody Titration: 1.0 μg/ml Positive Control: Mouse Pancreas
WB Suggested Anti-Uhrf2 Antibody Positive Control: Lane 1: 60ug HCT116 lysate Primary Antibody Dilution : 1:1000 Secondary Antibody : Anti rabbit-HRP Secondry Antibody Dilution : 1:5,000 Submitted by: Chinweike Ukomadu, Brigham and Women's Hospital, Boston |
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说明书 |
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数量 |
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