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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > Polyclonal Antibodies > Phospho-Ser394 HDAC2 Antibody

Phospho-Ser394 HDAC2 Antibody

货号 货期 规格 / 价格 询价
APR03406G 100 μl / ¥5450

Phospho-Ser394 HDAC2 Antibody

品牌

Leading Biology

货号

APR03406G

产品分类

Polyclonal Antibodies

研究领域

产品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Phospho-Ser394 HDAC2 Antibody.

分子量

55364 Da

宿主

Rabbit

种属反应性

Mouse

靶点

Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser394 of human HDAC2.

基因ID

UniProt ID

总结

Histone Deacetylase 2 (HDAC2) is part of a family of histone deacetylases that are responsible for deacetylation of lysine residues in the histone core. HDAC2 is classified as a class I histone deacetylase and is ubiquitously expressed throughout the body (Kee et al, 2008). It has been shown that HDAC2 plays an important role in cardiac hypertrophy (Eom et al, 2011). Phosphorylation of ser394 is responsible for the hypertrophy-associated activation of HDAC2, whereas intrinsic basal activity is maintained by phosphorylation of ser422 and ser424 (EOM et al, 2011).

储存条件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

应用

WB

稀释方法

WB~~ 1:1000

图像

Western blot of mouse heart lysate showing specific immunolabeling of the ~55k HDAC2 protein phosphorylated at Ser394 (control). Phosphospecificity is shown in the second lane (lambda-phosphatase: λ-Ptase). The blot is identical to the control except that the lysate was incubated in λ-Ptase (800 units/1mg protein for 30 min). The immunolabeling is completely eliminated by treatment with λ-Ptase.

说明书

数量

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