全部产品分类
品牌 |
Leading Biology | 货号 |
APR00092G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality HCAM Antibody.
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分子量 |
81538 Da
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细胞定位 |
Antigen Cellular Localization:
Cell membrane; Single-pass type I membrane protein. Note=Colocalizes with actin in membrane protrusions at wounding edges.
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宿主 |
Rabbit
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种属反应性 |
Human, Mouse, Rat
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靶点 |
HCAM
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亚型 |
Rabbit IgG
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通用名 |
LHR, MDU2, MDU3, MIC4
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基因ID |
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UniProt ID |
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功能 |
Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. In cancer cells, may play an important role in invadopodia formation. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events.
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总结 |
Cell adhesion molecules (CAMs) are a family of closely related cell surface glycoproteins involved in cell-cell interactions during growth and are tho μght to play an important role in embryogenesis and development. The CAM family includes NCAM (neuronal cell adhesion molecule), ICAM (intracellular adhesion molecule), PECAM (platelet/endothelial cell adhesion molecule), BLCAM (produced by alternative splicing of the CD22 gene), VCAM (vascular cell adhesion molecule), and HCAM (homing cell adhesion molecule, also designed CD44), etc.
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形式 |
Liquid
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC, IP
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说明书 |
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数量 |
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