全部产品分类
品牌 |
Leading Biology | 货号 |
APR03074G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality HEXIM1 Antibody (aa181-230).
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分子量 |
41kDa
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细胞定位 |
Antigen Cellular Localization:
Nucleus. Cytoplasm. Note=Binds alpha- importin and is mostly nuclear
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宿主 |
Rabbit
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种属反应性 |
Human, Mouse, Rat
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靶点 |
HEXIM1 Antibody detects endogenous levels of total HEXIM1 protein.
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通用名 |
CLP1, EDG1, HIS1, MAQ1
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基因ID |
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UniProt ID |
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功能 |
Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. In cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation. May also regulate NF-kappa-B, ESR1, NR3C1 and CIITA-dependent transcriptional activity.
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总结 |
Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. In cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation. May also regulate NF-kappa-B, ESR1, NR3C1 and CIITA-dependent transcriptional activity.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC-P, IF, E
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稀释方法 |
ELISA (1:10000), IF (1:100-1:500), IHC-P (20 μg/ml), WB (1:500-1:1000) ,
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图像 |
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说明书 |
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数量 |
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