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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > Polyclonal Antibodies > PBK / TOPK Antibody (aa1-50)

PBK / TOPK Antibody (aa1-50)

货号 货期 规格 / 价格 询价
APR02992G 50 μl / ¥4950

PBK / TOPK Antibody (aa1-50)

品牌

Leading Biology

货号

APR02992G

产品分类

Polyclonal Antibodies

研究领域

产品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PBK / TOPK Antibody (aa1-50).

分子量

36kDa

宿主

Rabbit

种属反应性

Human

靶点

PBK/TOPK (Ab-9) Antibody detects endogenous levels of total PBK/TOPK protein.

通用名

TOPK

基因ID

UniProt ID

功能

Phosphorylates MAP kinase p38. Seems to be active only in mitosis. May also play a role in the activation of lymphoid cells. When phosphorylated, forms a complex with TP53, leading to TP53 destabilization and attenuation of G2/M checkpoint during doxorubicin-induced DNA damage.

总结

Phosphorylates MAP kinase p38. Seems to be active only in mitosis. May also play a role in the activation of lymphoid cells. When phosphorylated, forms a complex with TP53, leading to TP53 destabilization and attenuation of G2/M checkpoint during doxorubicin-induced DNA damage.

储存条件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

应用

WB, IHC-P, E

稀释方法

ELISA (1:1000), IHC-P (5 μg/ml), WB (1:500-1:1000)

图像

Western blot of extracts from COS7 cells, treated with Nocodazole 1 ug/ml 16h, using PBK/TOPK...

Anti-PBK / TOPK antibody IHC of human thymus.

说明书

数量

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