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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > Polyclonal Antibodies > RAN Antibody (aa167-216)

RAN Antibody (aa167-216)

货号 货期 规格 / 价格 询价
APR02931G 50 μl / ¥4950

RAN Antibody (aa167-216)

品牌

Leading Biology

货号

APR02931G

产品分类

Polyclonal Antibodies

研究领域

产品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality RAN Antibody (aa167-216).

分子量

24kDa

细胞定位

Antigen Cellular Localization: Nucleus. Cytoplasm. Melanosome. Note=Predominantly nuclear during interphase (By similarity) Becomes dispersed throughout the cytoplasm during mitosis Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

宿主

Rabbit

种属反应性

Human, Mouse, Rat

靶点

RAN Antibody detects endogenous levels of total RAN protein.

通用名

ARA24

基因ID

UniProt ID

功能

GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle (By similarity). The complex with BIRC5/ survivin plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the RAN effector molecule TPX2 to microtubules. Acts as a negative regulator of the kinase activity of VRK1 and VRK2.

总结

GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle (By similarity). The complex with BIRC5/ survivin plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the RAN effector molecule TPX2 to microtubules. Acts as a negative regulator of the kinase activity of VRK1 and VRK2.

储存条件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

应用

WB, IHC-P, E

稀释方法

ELISA (1:10000), IHC-P (10 μg/ml), WB (1:500-1:1000)

图像

Western blot of extracts from LOVO cells, using RAN Antibody.

说明书

数量

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