品牌 |
Leading Biology | 货号 |
APR02684G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality FKTN / Fukutin Antibody.
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分子量 |
54kDa
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细胞定位 |
Antigen Cellular Localization:
Golgi apparatus membrane; Single-pass type II membrane protein
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宿主 |
Rabbit
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种属反应性 |
Human
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靶点 |
Human Fukutin. Predicted cross-reactivity based on amino acid sequence homology: mouse (90%), rat (91%).
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通用名 |
FCMD
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基因ID |
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UniProt ID |
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功能 |
Glycosyltransferase involved in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine- beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. May interact with and reinforce a large complex encompassing the outside and inside of muscle membranes. Could be involved in brain development.
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总结 |
Glycosyltransferase involved in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine- beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. May interact with and reinforce a large complex encompassing the outside and inside of muscle membranes. Could be involved in brain development.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC-P, IF, ICC
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稀释方法 |
ICC (1:100-1:200), IF (1:100-1:200), IHC-P (10 μg/ml), WB (1:500-1:3000) ,
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图像 |
Immunofluorescence of methanol-fixed HeLa, using Fukutin antibody at 1:200 dilution.
Sample (30 ug of whole cell lysate).
Anti-FKTN / Fukutin antibody IHC of human skeletal muscle. |
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说明书 |
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数量 |
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