品牌 |
Leading Biology | 货号 |
APR02530G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality GZMB / Granzyme B Antibody (N-Terminus).
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分子量 |
28kDa
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细胞定位 |
Antigen Cellular Localization:
Cytoplasmic granule. Note=Cytoplasmic granules of cytolytic T-lymphocytes and natural killer cells
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宿主 |
Rabbit
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种属反应性 |
Human, Mouse, Rat
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通用名 |
CGL1, CSPB, CTLA1, GRB
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基因ID |
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UniProt ID |
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功能 |
This enzyme is necessary for target cell lysis in cell- mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
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总结 |
This enzyme is necessary for target cell lysis in cell- mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
IHC-P
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稀释方法 |
IHC-P (1:100)
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图像 |
Anti-GZMB / Granzyme B antibody IHC of human spleen. |
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说明书 |
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数量 |
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